Lion's Mane
Hericium erinaceus
Medicinal mushroom used for cognitive support. No FDA RDI; declared with † symbol. Common extracts: 10:1, 8:1 dual extract.
FDA Reference Data
About Lion's Mane
Lion's Mane (Hericium erinaceus) is a medicinal mushroom traditionally used in East Asian medicine for cognitive support. As a botanical ingredient, it has no FDA-established RDI and is declared with the † symbol on Supplement Facts labels. Common extract specifications include 10:1 hot water extract (concentrating beta-glucans) and 8:1 dual extract (alcohol + water, capturing both water-soluble and alcohol-soluble compounds). The fruiting body is the primary plant part used; mycelium is sometimes included in dual extracts.
Common Supplement Forms
Frequently Asked Questions
How do I declare Lion's Mane extract ratio on my Supplement Facts label?
The extract ratio (e.g., 10:1) may be declared as part of the ingredient name in the ingredient list (e.g., "Lion's Mane (Hericium erinaceus) Fruiting Body Extract (10:1)"). The Supplement Facts panel itself declares the amount in mg with the † symbol (no %DV). The Latin binomial and plant part (fruiting body or mycelium) are required per FDA 21 CFR 101.36(z).
What is the difference between Lion's Mane fruiting body and mycelium?
The fruiting body (mushroom cap and stem) contains hericenones; the mycelium (root-like network) contains erinacines. Both compounds are studied for nerve growth factor (NGF) stimulation. Fruiting body extracts are more traditional; mycelium extracts may offer complementary compounds. Some products combine both for full-spectrum effect, which should be declared on the ingredient list.
What's the difference between 10:1 and 8:1 Lion's Mane extracts?
10:1 typically refers to a hot water extract (10 kg raw mushroom concentrated to 1 kg extract), preserving beta-glucans and polysaccharides. 8:1 usually refers to a dual extract (alcohol + water), which additionally captures alcohol-soluble compounds like hericenones and erinacines. The choice depends on formulation goals: 10:1 emphasizes immune-supporting polysaccharides; 8:1 emphasizes nootropic compounds.
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