Vitamins

Biotin

Vitamin B7

Water-soluble B-vitamin for hair, skin, and nail health. FDA RDI 30 mcg/day. Common in beauty and beauty-from-within supplements.

FDA Reference Data

RDI (Adults 4+)
30 mcg
Unit
mcg
Mandatory Declaration
No (voluntary)
Regulation
21 CFR 101.36

About Biotin

Biotin (vitamin B7) is a water-soluble B-vitamin that supports keratin infrastructure for hair, skin, and nails. FDA RDI is 30 mcg/day for adults 4+. Biotin is voluntary on Supplement Facts but commonly used at 2,500-10,000 mcg (83x-333x RDI) in beauty supplements. Important labeling caution: high-dose biotin (5,000+ mcg) can interfere with lab tests (troponin, TSH, hCG) — labels may require a "Biotin may interfere with lab tests" warning statement.

Common Supplement Forms

D-Biotin
Natural form; 100% bioavailable; the only form used in supplements.

Note: When a salt form is used, the Supplement Facts panel must declare the elemental amount (e.g., “Magnesium 141 mg 34%”), not the salt weight. The salt name appears in the ingredient list below the panel. See %DV calculator for calculation details.

Frequently Asked Questions

What is the FDA RDI for biotin?

The FDA RDI for biotin is 30 mcg per day for adults and children 4 years and older (21 CFR 101.9(c)(8)(iv)). %DV on Supplement Facts labels is calculated as: (declared biotin / 30) × 100, rounded to the nearest whole percent.

Why is biotin used at doses much higher than the RDI?

Hair, skin, and nail supplements typically use 2,500-10,000 mcg of biotin (83-333x the RDI) based on cosmetic effect studies. There is no established toxicity threshold for biotin, and excess is excreted in urine. High-dose biotin (≥5,000 mcg) is the standard in beauty-from-within formulations.

Does biotin interfere with medical lab tests?

Yes. FDA issued a safety communication in 2017 (updated 2019, 2024) warning that biotin can cause falsely high or falsely low results on common lab tests including troponin (heart attack diagnosis), TSH (thyroid function), and hCG (pregnancy). Supplement labels for products containing >1,000 mcg biotin should include a warning statement about potential lab test interference.

Building a supplement with Biotin?

ReguSift extracts ingredients from your COA, calculates %DV, formats proprietary blends, and generates a print-ready Supplement Facts label — including Biotin auto-formatted per FDA 21 CFR 101.36.

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